Denali Therapeutics Inc., discovers, develops, and delivers barrier-crossing therapeutics for neurodegenerative, lysosomal, and other serious diseases in the United States. The company's transport vehicle (TV)-enabled programs include DNL310 ETV, an IDS enzyme replacement therapy program for MPS II; TAK-594/DNL593 which is in Phase 1/II for frontotemporal dementia-granulin; DNL126 program for MPS IIIA; and DNL622 for MPS I. Its brain-penetrant small molecule programs comprise BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; DNL343 eIF2B Activator program for amyotrophic lateral sclerosis; and SAR443122/DNL758 RIPK1 inhibitor program for peripheral inflammatory diseases. It also provides early stage program include TAK-594/DNL593 program for FTD-GRN; DNL126 program for MPS IIIA, a Sanfilippo Syndrome A; DNL622 for MPS I which is Hurler syndrome; DNL921 Antibody Transport Vehicle Amyloid beta program; Oligonucleotide Transport Vehicle platform, a novel class of biotherapeutics to address the root cause of diseases through modulation of gene expression; and other TV-enabled discovery programs. The company has collaboration agreements with Biogen MA Inc. and Biogen International GmbH; Genzyme Corporation; Takeda Pharmaceutical Company Limited; F-star Gamma Limited, F-star Biotechnologische Forschungs-und Entwicklungsges m.b.H, and F-star Biotechnology Limited; and Genentech, Inc. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

Denali Therapeutics Inc.

Denali Therapeutics ( ($DNLI) ) has shared an announcement. On April 3, 2026, Denali Therapeutics said Takeda Pharmaceutical will terminate their 2...

Denali Regains DNL593 Rights After Takeda Collaboration Ends

Denali Therapeutics ( ($DNLI) ) just unveiled an update. Denali Therapeutics Inc. secured $200 million in gross proceeds on March 27, 2026, upon cl...

Denali Therapeutics Secures $200 Million Royalty Funding

In a report released today, Paul Matteis from Stifel Nicolaus maintained a Buy rating on Denali Therapeutics, with a price target of $41.00. Mattei...

Stifel Nicolaus Sticks to Its Buy Rating for Denali Therapeutics (DNLI)

In a report released today, from Jefferies maintained a Buy rating on Denali Therapeutics, with a price target of $40.00. In addition to Jefferies,...

Jefferies Sticks to Its Buy Rating for Denali Therapeutics (DNLI)

There’s a lot to be optimistic about in the Healthcare sector as 2 analysts just weighed in on Theravance Biopharma (TBPH) and Denali Therapeutics ...

Wall Street Analysts Are Bullish on Top Healthcare Picks

An update from Denali Therapeutics ( ($DNLI) ) is now available. On March 25, 2026, Denali Therapeutics announced that the U.S. Food and Drug Admin...

Denali Therapeutics Gains FDA Approval for AVLAYAH Therapy

There’s a lot to be optimistic about in the Healthcare sector as 2 analysts just weighed in on Denali Therapeutics (DNLI – Research Report) and Oru...

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1	Symbol	Price	Change	Volume
2	DNLI	$19.29	0.00%	1.44M
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	A	B	C	D
1	Symbol	Price	Change	Vol
2	DNLI	$19.29	0%	1.44M
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